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Blood Test Might Help Tell When Peanut Allergy Is Gone: Study

FRIDAY, Jan. 31, 2014 (HealthDay News) -- A type of treatment to help build up resistance in people with peanut allergy might leave telltale signs in the people's immune-system DNA, a new study reveals.

The findings suggest that a blood test for these DNA changes could be used to monitor the long-term effectiveness of so-called "immunotherapy" in patients allergic to peanuts, according to the researchers.

There is no cure for peanut allergy, but researchers are examining whether consuming increasing amounts of peanut powder helps desensitize people to the peanut allergen. After participating in this doctor-supervised therapy, patients typically are told to eat some peanuts every day for the rest of their lives.

However, it's not possible to test patients to determine if they can safely stop eating peanuts every day, study senior author Dr. Kari Nadeau, an associate professor of pediatrics at the Stanford University School of Medicine, said in a university news release.

"At first, eating two peanut butter cups a day might seem fun, but it gets a little boring and a lot of people might stop," said Nadeau, who also is an immunologist at Stanford Hospital and Clinics and the Lucile Packard Children's Hospital. "Our new finding can help us try to determine whether, for the long term, someone's allergy has truly been shut off so people can eat ad lib."

The study included 20 children and adults with peanut allergy who had spent two years building up their immunity. They were able to eat a 4-gram serving of peanuts each day without suffering a severe allergic reaction.

The participants were told to avoid peanuts for three months, and then the researchers gave them a small amount of peanut powder to determine if their allergy had returned. The allergy came back in 13 patients, while seven remained allergy-free, the study authors said.

The researchers then analyzed blood samples taken from these two groups, as well as from people with peanut allergy who had never received oral immunotherapy. The investigators found that the DNA in white blood cells, which help reduce allergy response, was different in each of the three groups of patients.

Nadeau said this test might one day help doctors in deciding whether a person "can safely go off of immunotherapy, or if they need to continue to eat the food every day." It could also help determine whether a person might benefit from a longer course of immunotherapy, she said, but more study is needed.

The study was published online Jan. 31 in the Journal of Allergy and Clinical Immunology.

More information

Food Allergy Research and Education has more about peanut allergy.

Black Children, Teens More Likely to Return to Hospital for Asthma: Study

MONDAY, Feb. 3, 2014 (HealthDay News) -- Financial and social hardships are the major reasons black children and teens are twice as likely as whites to be readmitted to the hospital for asthma, a new study suggests.

Researchers looked at nearly 800 asthma patients, aged 1 to 16, who were admitted to Cincinnati Children's Hospital Medical Center between August 2010 and October 2011. Fifty-seven percent of the patients were black.

Overall, 19 percent of the children were readmitted to the hospital within a year. This included 23 percent of blacks and 11 percent of other children, most of whom were white, according to the study, which was published online Feb. 3 in the journal Pediatrics.

Caregivers of black children were much more likely to say they had financial and social hardships, such as being jobless and not having a car. These hardships accounted for about 40 percent of the racial disparity in asthma readmissions.

"Reducing disparities in such outcomes will be critical, especially since payment reform will be based more on quality outcomes and less on health care encounters," study author Dr. Andrew Beck, a pediatrician at Cincinnati Children's, said in a hospital news release.

"Our findings suggest that a more intense patient- and population-level focus on the financial and social hardships that underlie racial disparities may provide one path for achieving better outcomes," Beck said.

Study senior author Dr. Robert Kahn, a pediatrician at Cincinnati Children's, said there is great potential to make changes to existing clinical practices.

"Transportation barriers might be addressed with home delivery of medications, job barriers with a connection to job training and both helped by a community health worker," Kahn said. "The goal would be upstream, community-based prevention, rather than paying for readmissions."

Other factors that might explain why black children and teens with asthma are more likely to be readmitted to the hospital include pollution, exposure to secondhand smoke and poor living conditions, Beck said.

More information

The U.S. National Heart, Lung, and Blood Institute has more about asthma.

More Pesticides Linked to Parkinson's Risk

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Climate Change Predicted to Boost Heat-Related Deaths

As Wintertime drags on, Lots of people mature weary of frigid temperatures, ice and snow. For them, The excellent news is that summer season is simply within the corner.The poor news is, there may very well be a tremendous increase in heat-similar deaths during the summer months in the approaching many years, a brand new review suggests.The quantity of deaths a result of sizzling weather in England and Wales could practically triple by the center of your century, according to scientists.This sharp spike in deaths will likely be resulting from The mix of local weather transform and an aging inhabitants, said Dr. Shakoor Hajat and colleagues in the London University of Hygiene and Tropical Medicine, and General public Well being England.

The investigators analyzed details on weather patterns and Dying premiums from 1993 to 2006 and used it to projected climate alterations and inhabitants raises in the 2020s, 2050s and 2080s. They concluded that the number of hot times in England and Wales will triple because of the mid-2080s, and the number of chilly times will reduce.If no adaptive measures are taken, The present variety of 2,000 heat-connected deaths a 12 months in England and Wales will increase 257 percent through the 2050s, when the current variety of 41,000 deaths from chilly will tumble two p.c on account of milder winters, the researchers predicted.


Despite the fact that more people will continue to die as a consequence of chilly weather conditions than hot temperature, rising temperatures will turn out to be expanding deadly, specifically for the aged. Individuals aged 75 and older is going to be at finest threat for heat-connected death, in accordance with the review released on line Feb. three in the Journal of Epidemiology and Community Health.The findings reveal that security from warm climate will come to be most significant for people aged eighty five and more mature, partly because people are living longer which group could make up a rising proportion of your elderly populace.

Along with air-con, preventive steps could contain much more sustainable possibilities such as shading and adjustments in making insulation and development supplies, the analyze authors observed inside of a journal news release.

Extra informationThe U.S. Centers for Ailment Handle and Avoidance provides very hot temperature tips.

Old Wood Stoves a Costly Way to Keep Warm

Although A lot of people use indoor and out of doors wood heaters to economize on fuel costs, burning Wooden to remain heat through the cold winter months might not be Price tag-productive, based on the U.S. Environmental Safety Company.The company also cautioned that smoke from older wood stoves may possibly pose a significant wellbeing threat by rising air pollution from soot and harmful pollutants. Soot, generally known as fine particle pollution, has been linked to several health conditions, which includes heart attacks, strokes and bronchial asthma.



The EPA discussed in an agency information launch that previous, uncertified Wooden stoves give off additional air air pollution than pellet or fuel heaters. On top of that, up-to-date EPA-Licensed Wooden stoves use a person-third less Wooden than older styles and make approximately sixty per cent considerably less air pollution although generating the identical volume of warmth.EPA authorities also reported most hydronic heaters, which typically burn Wooden outdoors a house to heat water which is piped inside, are fewer successful than other household-heating appliances. Many of these heaters may also produce an extreme degree of smoke, that may negatively have an effect on neighbors.

The EPA proven a system during which companies can voluntarily make cleaner variations of hydronic heaters. The more recent products ensuing from this software are approximately ninety p.c cleaner than more mature appliances.

You'll find about 10 million wood stoves and a lot more than 240,000 hydronic heaters in The usa, the EPA said from the news release. The company is encouraging alter-out applications that may aid consumers in trading within their old, inefficient Wooden-burning appliances for more recent versions.



The EPA also issued a proposal to update criteria For brand new Wooden stoves and heaters. Below these revised rules, the subsequent era of appliances could well be an approximated eighty p.c cleaner compared to models at this time being built.A community Listening to is scheduled to take place on Feb. 26 in Boston. The EPA said it hopes to obtain the public's enter on its proposal.In an effort to melt away wood more safely and competently, the EPA also offered the next suggestions:Burn up only effectively-seasoned wood.Under no circumstances burn off trash or garbage.Hardly ever burn up demolition debris.

The Weather Affect Your Stroke Risk

 Imagine hearing a weather forecaster warn that tomorrow could be "colder with a chance of stroke."As odd as that may seem, researchers have found possible associations between certain weather conditions and the incidence of strokes.Larger daily temperature variations and higher humidity each were associated with higher stroke hospitalization rates, according to a new study.The researchers also found that colder average annual temperatures were associated with stroke hospitalizations and death. An average daily temperature change of 5 degrees Fahrenheit was associated with about a 6 percent increase in stroke risk and hospitalization, the researchers said.

The reasons behind the findings are unclear, said study lead author Judith Lichtman. And although the study showed an association between weather and stroke risk, it didn't prove a cause-and-effect relationship."Daily fluctuations in temperature and increased humidity may actually be stressors," said Lichtman, an associate professor of epidemiology at the Yale School of Public Health. "People at risk for stroke may want to avoid being exposed to significant temperature changes and high humidity."How might fluctuating temperatures actually stress the body? When temperatures go down, blood vessels in the skin constrict so the body doesn't waste a lot of heat, said Dr. Mark Stecker, chairman of the department of neurosciences at Winthrop-University Hospital in Mineola, N.Y. When it's warm outside, the vessels open up to increase heat loss through the skin.

Stecker, who was not part of the research team, said the idea that weather can affect health is not new. "People think there should be a relationship," he said. "They often say things like, 'My joints hurt -- maybe it's going to rain,' or, 'I got a cold because it's cold outside.'"There might be something to old wives' tales, he said, but it's extremely difficult to know for sure.The study, which is scheduled for presentation Wednesday at the American Stroke Association meeting in San Diego, should be considered preliminary until published in a peer-reviewed journal.For the research, Lichtman and her team used 2009-10 statistics from a national database on hospital inpatients, noting ischemic stroke hospitalizations of people 18 years old or older. Ischemic strokes happen as a result of an obstruction within a blood vessel supplying blood to the brain. The new study included data from nearly 135,000 patients.

Temperature and dew point were pulled from the U.S. National Climatic Data Center and linked to stroke discharges at the county level. Factors such as region, season, age, gender, race and patient health issues (such as diabetes and high blood pressure) were considered in the analysis of the data.This study isn't the first to suggest a relationship between weather and stroke risk, Lichtman said. She said other studies done in Europe and Japan have shown seasonal associations for weather and stroke.Lichtman suggested that people at risk of stroke who are living in a region with extreme weather fluctuations might want to minimize their exposure to the extremes. That might be as simple as staying indoors with air conditioning on a hot day or ensuring ample heating when it's especially cold outside, she said.

Fluctuating or extreme weather conditions should also raise alertness for the signs and symptoms of stroke, Lichtman said.For his part, Stecker said the research will have a minimal impact on managing stroke risk."I'd tell a patient to not even think about it. People have enough anxiety already," he said. It's more important to focus on other risks, such as diet, weight, blood pressure, exercise and whether they take a statin to treat high cholesterol, he said.Lichtman said she wants to do more research to better understand whether there is a more defined cause-and-effect relationship between weather and stroke risk, and explore the cause in more depth. "Understanding the reasons for the associations between weather conditions and stroke could lead to the development of targeted preventive interventions," she said.Lichtman, who is married to a musician, said she knows firsthand how weather can affect us. "My husband's violin responds to extreme weather temperatures and humidity all the time," she said.

Healthy Eating Plan Blog

 Everyone trying to lose weight (and failed) many times asked himself this question – why? The rules seam simple - eat healthy food and exercise – that’s it. In real life it gets complicated though – there is always some excuse, some reason, some temptation we cannot resist. There is more to it as we know that there are different body types, we all have different genetics and metabolism. On top of that (if that’s not enough) many of us have weak willpower and what we plan does not always work out well in practice. So where do we start? Well I am in process of fast weight loss of 20kg (5kg gone so far in 26 days) and trust me I don’t have the strongest willpower nor can I resist temptation (today hot & spicy wings + barbecue ribs were delicious).

Healthy Eating Plan Blog

I will be honest with you – I failed many times, but what keeps me going is constant motivation. Whatever works for you – stick to it. Let me give some examples that I use – look in the mirror every time you want to eat something, grab your tummy and think about what you want – suffer for couple weeks and then feel and look good for years or grab something quick, eat it in 5 minutes and then feel bad about it. Distract yourself – play game, watch movie, go out to supermarket to buy some magazine – walking will burn calories.

Weight Loss Resources

 

With so many products, techniques, diets and solutions on the market – who wouldn’t have a headache just from checking some of them. That’s why I’ve created this page and this whole site – to give you my personal, honest opinion on the matter. You don’t know me, you’re not sure if I just want to cheat and lie to you and you can be thinking of leaving this page by now but let me tell you this – if you’re here then you’re in the same position as I am - need to loose weight fast and keep it that way.So as I’ve mentioned there are many weight loss resources out there and trust me - I’ve tried a lot of them with very bad results indeed. Lately I’ve come across Fat Loss Factor program – it is on the market for a while now and in my opinion it just adds credibility to it. If it would be bad then it would disappear from the market long time ago.

It is a very interesting and complex program which can be customized to basic needs as well as advanced ones. What I mean by that is for example I use basic path in it where I check my weight and follow the plan (4 phases in total) but you can also have online daily weight input, diet plan for the whole week prepared by Weight Loss Resources

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